The Heart and Stroke William L. MacDonald lectureship series was established in 1970 by the Board of Directors of the Heart and Stroke Foundation (previously known as Ontario Heart Foundation) in memory of the President of the Board, William L. MacDonald. The lectureship, presented annually at one of the six medical schools in Ontario, provides an opportunity for the research community and clinicians to share and discuss the latest issues with leaders in the cardiovascular field.
This year's Heart and Stroke MacDonald lectureship will be delivered by Dr. Douglas L. Mann, Chief of Cardiology at the Washington University School of Medicine, who will be speaking on the Role of Innate Immunity on Cardiac Injury and Repair.
Dr. Mann is the Lewin Chair and Professor of Medicine, Cell Biology and Physiology, Chief of the Division of Cardiology at the Washington University School of Medicine, and Cardiologist in Chief at Barnes-Jewish Hospital in St. Louis.
About the lecture:
The Role of Innate Immunity in Cardiac Injury and Repair
This talk will review the studies that suggest that heart has intrinsic “hard-wired” repair systems that were designed to lead to repair and/or regeneration of cardiac tissue. However, when this intrinsic repair system is excessively activated for a prolonged period of time, it can lead to adverse consequences, including dilation and dysfunction of the heart that lead, ultimately to the development of heart failure.