Too Much Sodium Linked to 1.65 Million Deaths Annually
According to a recent Harvard University study, each year 1.65 million people die worldwide from high-sodium diets that lead to heart disease, stroke and other cardiovascular disease. The review of existing research found that most people eat far more salt than recommended, and salt is a major
Researchers Uncover Mechanism Used by the Brain to Control Blood Pressure
For decades, researchers have known that the brain controls the diameter of the peripheral arteries, the vessels that carry blood to the arms, legs, hands and feet. Electrical impulses from the brain travel to these arteries through a network of nerves known as the sympathetic nervous system
Cholesterol-Elevating Protein Linked to Heart Attack
At the big-picture level, we understand the risk factors for a heart attack, including high cholesterol, high blood pressure, diabetes, smoking, and genetics. We also know that a heart attack is caused when plaque buildup in the wall of a coronary artery ruptures and blocks the blood vessel. What
A Passion for the Intimate Details of a Protein
Researcher Thomas Lagace, PhD, first came across the protein PCSK9 as a postdoctoral fellow, never guessing that it would become the focus of his career. While starting his post-doc at University of Texas Southwestern Medical Center, he was placed “kind of kicking and screaming,” as he put it, on a
Most Canadian Women Are Unaware of the Symptoms and Risk Factors of Heart Disease
The good news is that their hearts are in the right place. Women in Canada see themselves as their families’ “heart keepers,” playing a significant role in maintaining everyone’s heart health, whether it’s the food they serve, the physical activity they encourage, or the non-smoking households they
Women and Heart Disease
[Editor’s note: This article is an update of a previously published story.] Heart disease is the leading cause of death for women worldwide, yet it remains under-diagnosed and symptoms often go unrecognized. In July of this year, the Canadian Women’s Heart Health Centre published the results of a
Surviving and Thriving with Adult Congenital Heart Disease
[Editor’s note: This article is an update of previously published story.] Nearly one in every 100 babies is born with some form of congenital heart disease (CHD). In the 1950s, only about 15% of these children with severe heart defects reached their 18th birthday. Today, with advances in treatment
Function Found for Mysterious Heart Disease Gene
Finding a gene associated with disease is one thing. Understanding how it increases the likelihood of contracting that disease can be quite another, especially a complex condition like heart disease. After five years, Heart Institute researchers now know how one genetic variant works and suspect
A Snapshot of the State of Personalized Cardiovascular Care
The second annual Ottawa Heart Research Conference convened on May 8, bringing together an enthusiastic community of scientists and trainees to share insights on personalized cardiovascular medicine. The theme was chosen in honour of former University of Ottawa Heart Institute President and CEO
Looking to the Future of Cardiovascular Genetics Research
The past decade has seen rapid progress in cataloguing the genetic factors driving heart disease risk. The University of Ottawa Heart Institute led the way, discovering the first and, to date, highest-impact common genetic variant linked to coronary artery disease. Many others have been found since