A class of anti-cholesterol drugs called PCSK9 inhibitors has been in the press lately, and for good reason: they can reduce blood cholesterol levels substantially beyond what a statin alone can achieve. Two have made it to market so far for treating coronary artery disease, with more likely to come...
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The past decade has seen rapid progress in cataloguing the genetic factors driving heart disease risk. The University of Ottawa Heart Institute led the way, discovering the first and, to date, highest-impact common genetic variant linked to coronary artery disease. Many others have been found since...
It was Anne McAllister, a 56-year-old lawyer living in Ottawa who first sparked Dr. David Birnie’s interest in a rare but potentially deadly heart condition just over a decade ago. McAllister was experiencing frequent spells of arrhythmia. Her heart rate changed from rapid to slow without any...
Broadly speaking, Canadians at risk for a heart attack know they need to improve their physical health. But not all do. In a recent study of residents of six Canadian provinces, almost one in five people with the highest cardiac risk did not think they needed to make any lifestyle changes to improve...
There are several inherent differences to the physical make up of a woman’s heart versus that of a man. For starters, a man’s heart is physically larger, weighing up to 60 grams more than a woman’s heart on average. Functionally there are differences, too. Arteries which feed a women’s heart with...
A renowned cardiac surgeon, a champion of innovation, and an experienced and respected administrator, Dr. Thierry Mesana is also a passionate advocate for the University of Ottawa Heart Institute. On September 11, the Heart Institute announced his appointment as its third President and CEO, to...
With populations aging in much of the world, the decline of mental capacity in later years is of increasing concern. There has been hope in the medical community that effectively treating high blood pressure and atherosclerosis could slow or delay this decline. In a study of people over the age of...
It has been little more than a decade since researchers categorized the full suite of genes contained in the human body, but this exciting milestone merely opened up an even more challenging frontier. There turns out to be only about 20,000 genes associated with the famous DNA molecule—a sizable...
February is Heart Month, and the federal Minister of Health, the Honourable Jane Philpott, chose to kick it off by coming to the Ottawa Heart Institute to announce $2.9 million in funding for five of its researchers. Heart disease is the second-leading cause of death in Canada. This funding, through...
The good news is that their hearts are in the right place. Women in Canada see themselves as their families’ “heart keepers,” playing a significant role in maintaining everyone’s heart health, whether it’s the food they serve, the physical activity they encourage, or the non-smoking households they...
Shoehorned into a small room, the first positron emission tomography (PET) scanner at the University of Ottawa Heart Institute made possible a dedicated PET imaging service for heart patients one day a week. That was in 1995, and cardiologist Rob Beanlands, MD, physicist Rob deKemp, PhD, and nuclear...
With roughly half a million Canadians now living with heart failure, the condition is an increasingly common one that can seriously impact an individual’s quality of life. Even when appropriately treated, hospital admission and readmission rates are stubbornly high. George Wells, Director of the...
Arrhythmias — disturbances of the heart’s normal rhythm—affect more than 1.5 million Canadians and can impact a person’s health and well-being in a variety of ways. Sudden cardiac death caused by an arrhythmia kills 40,000 people every year. An estimated 350,000 Canadians are living with atrial...
More than half a million Canadians are living with heart failure and another 50,000 join their ranks each year. The standard treatment for heart failure has not changed for quite some time. Now, a new drug—so new that it’s identified only as LCZ696—is generating interest among cardiologists and...
Not all treatments work in all patients, but often it’s not possible to know ahead of time who will benefit. The Ottawa Heart Institute recently became the first centre in Canada to use a new radioactive tracer clinically to better define the prognosis of a patient in heart failure. The tracer...
In less than a decade, the search for common genetic variations that alter people’s risk of disease has changed the way we think about genetic risk. In the world of cardiovascular medicine, 36 single-nucleotide polymorphisms (SNPs)—the tiny genetic changes that help to differentiate one individual’s...
All exercise is good, and some is better than none, but the health benefits of Nordic walking are superior, study finds. Cardiovascular rehab programs and exercise in general is known to improve the health of people with heart disease. However, less is known about whether such improvements are...
Nurses make up the largest professional group within the healthcare workforce and their work is perceived as being physically and mentally demanding. According to a National Survey of the Work and Health of Nurses in Canada conducted in 2005, an alarming proportion of Canadian nurses then reported...
Occupational therapy is proving to be one of the most important ways to avoid readmission to hospital. This was the finding of a study recently published in the journal Medical Care Research and Review which found readmission rates for heart patients were lower in hospitals that invested more in...
Cardiovascular disease is the world’s leading cause of death, but there are many behaviours you can change to decrease your risk of having a heart attack or stroke. Online cardiovascular calculators, powered by big data and artificial intelligence (AI), are making it easier than ever before to help...