No lions, giraffes, or hippopotami were observed during a SAFARI led by doctors at the University of Ottawa Heart Institute (UOHI). However, doctors did get an unexpected surprise: important new insight into how best to treat patients after a severe heart attack. Thanks to the SAFARI-STEMI trial, a...
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On January 1, 2013, Dr. Marc Ruel took over as Chief of Cardiac Surgery at the University of Ottawa Heart Institute. He succeeded Dr. Thierry Mesana, who had led the division since 2001. Since joining the Heart Institute in 2002, Dr. Ruel has been a pioneer and advocate of minimally invasive cardiac...
Experts at the University of Ottawa Heart Institute (UOHI) are using the motto “Less is best” in discussions with patients about alcohol and heart health.
Exciting medical discoveries are being fed through our social media feeds and television screens with a seemingly limitless speed and diversity. From breakthroughs like genetic engineering and regenerative medicine to emerging technologies like artificial intelligence and robotic surgery, we live in...
Nanotechnology is a rapidly growing science of producing and utilizing nano-sized particles invisible to the naked eye. In biomedicine, nanosilver is one of the most studied nanomaterials because of its natural antibacterial, antifungal, and even anti-inflammatory properties. Also, due to its unique...
Data scientists at the University of Ottawa Heart Institute (UOHI) have developed and tested a clinical model to accurately predict the risk of death and unplanned cardiac hospitalization for patients awaiting heart surgery. Unplanned cardiac hospitalization refers to nonelective (urgent) admission...
Scientists at the University of Ottawa Heart Institute (UOHI) have developed a promising new therapy that successfully targets methylglyoxal (MG), a molecule that “toxifies” the heart following a heart attack, according to a study published in Advanced Functional Materials. Under normal conditions...
Cardiovascular implantable electronic devices (CIED) save lives – there’s no question about it. But, on rare occurrences, infections can lead to serious, often life-threatening complications. Last year, it was determined by science that more aggressive use of antibiotics around the time of device...
Oily fish is widely recommended as part of a heart-healthy diet, based in part on a landmark study from the 1970s. In it, Danish researchers Hans Olaf Bang and Jørn Dyerberg connected the low incidence of coronary artery disease (CAD) among the Inuit of Greenland (referred to as Eskimos in the study...
COVID-19 wasn’t about to shut down Canada’s largest gathering of cardiovascular specialists and allied health professionals. Last month, as public health officials introduced restrictions to prevent mass get-togethers in regions across the country, heart-focused members of the medical community were...
Shortness of breath, swelling ankles, fatigue—they can easily be passed off as part of getting older. But for more than 600,000 Canadians, these are signs of something much more serious. They are among the frustratingly non-specific symptoms of heart failure, the only form of heart disease that is...
Last year, research established heart failure-associated deaths and hospitalizations are higher in women than in men. Today, new research from the University of Ottawa Heart Institute (UOHI) suggests women are also faring worse than men when it comes to their chances of long-term survival after...
Traditionally, frailty is thought to be a syndrome of the elderly – one which comes as a natural and inevitable side-effect of aging, gradually transforming strong, healthy bodies into weaker, more delicate frames over time. For clinicians, frailty is a concept which has long posed formidable...
Finding a gene associated with disease is one thing. Understanding how it increases the likelihood of contracting that disease can be quite another, especially a complex condition like heart disease. After five years, Heart Institute researchers now know how one genetic variant works and suspect...
March 8th is International Women’s Day, a day where women are globally recognized for their contributions and advancements in society. But could their next battle be against gender biases in the way society cares for them? Due to barriers in sport and physical activity over the last century, many...
In its simplest incarnation, CRISPR-Cas9 is a wildly popular and powerful gene-editing technology which can be thought of as a two-part machine – one that essentially works as a find-and-replace or find-and-remove for your DNA. The first part of the CRISPR-Cas9 machine is the guide RNA, a short...
Dr. Frans Leenen is the Director of the Hypertension Clinic and Hypertension Research at the University of Ottawa Heart Institute. In 2008, he and fellow Heart Institute researcher Dr. George Fodor led the Ontario Survey on the Prevalence and Control of Hypertension, the most in-depth study of high...
The latest global ranking of research organizations from Scimago Institutions Rankings (SIR) recognizes the continued excellence and vitality of research at the University of Ottawa Heart Institute, placing it 159th out of 4,851 institutions worldwide, across all fields of study. In Canada, the...
Every research institute is driven by its army of graduate students and post-doctoral fellows. They bring their enthusiasm and curiosity to the lab each day and create new collaborative relationships between research groups, both down the hall and around the globe. The Beat spoke with four graduate...
It was a cold, wintery morning on January 15 when a crowd of well-wishers joined numerous city and provincial dignitaries to celebrate the groundbreaking for the University of Ottawa Heart Institute’s expansion project. Many years in the making, the expansion will have a substantial impact on the...